Treatment-Resistant Depression (TRD) Treatment

Treatment-Resistant Depression (TRD) Treatment in Seattle, WA

What Is TRD?

Treatment-Resistant Depression (TRD) is when depression does not improve after trying at least two different antidepressants. TRD can feel especially isolating—but there are still effective options available.

Types of TRD

TRD may present as:

• ‍Primary TRD: Never responding to medications‍
• Secondary TRD: Responding initially, then losing effect‍
• Depression with anxiety or PTSD: Making it harder to treat‍
• TRD with bipolar disorder or other conditions
  
  

What Are the Symptoms ofTRD?

In Adults:

• Sadness that doesn’t go away
• Hopelessness or suicidal thoughts
• Low energy and fatigue
• Trouble sleeping or excessive sleeping
• Lack of interest in things you used to enjoy
  
  

In Children:

• Persistent irritability or sadness
• Poor school performance
• Social withdrawal
• Changes in appetite or sleep
• Frequent complaints of physical illness
  
  

TRD and Relationships

Long-term depression can strain relationships. You may feel:

• Disconnected or misunderstood
• Guilt or shame for how you feel
• Unable to express emotions
• Overwhelmed by day-to-day tasks 
• Unsupported even by those who care
  

Coping Skills for TRD

Coping with TRD is hard, but small steps can help:

• Sticking to a routine
• Setting small, achievable goals
• Practicing self-kindness and patience
• Staying connected with a support system
• Joining support groups or therapy sessions
  
  

How TMS and Spravato® CanHelp

TMS Therapy for TRD

TMS is FDA-approved for depression and particularly helpful for those who have tried medications with little to no success. It stimulates under active brain areas linked to mood and motivation.

TMSBenefits:

• Non-invasive and medication-free
• Improves mood, sleep, and daily function
• Long-term symptom relief for many patients
  

Spravato® for TRD

Spravato®(esketamine) is FDA-approved specifically for TRD. It works differently from standard antidepressants and may bring fast symptom relief.

Spravato® Benefits:

• Rapid reduction of depressive symptoms
• May help when other treatments have failed
• Can reduce suicidal thoughts quickly
  

Find Hope with Clear PathPsychiatry

You don’t have to live with untreated depression. Our team in Seattle provides evidence-based care for TRD using TMS and Spravato® to help you feel like yourself again.

📍 Serving patients in Seattle and surrounding areas.

📍 Call 206-486-8150 for inquiry